Tobacco mosaic virus has served as a model organism for pathbreaking work in plant pathology, virology, biochemistry and applied genetics for more than a century. We were intrigued by a photograph published in Phytopathology in 1934 showing that Tabasco pepper plants responded to TMV infection with localized necrotic lesions, followed by abscission of the inoculated leaves. This dramatic outcome of a biological response to infection observed by Francis O. Holmes, a virologist at the Rockefeller Institute for Medical Research, was used (...) to score plants for resistance to TMV infection. Our objective was to gain a better understanding of early to mid-twentieth century ideas of genetic resistance to viruses in crop plants. We investigated Holmes’ observation as a practical exercise in reworking an experiment, having been inspired by Pamela Smith’s innovative Making and Knowing Project. We had a great deal of difficulty replicating Holmes’ experiment, finding that biological materials and experimental customs change over time, in ways that ideas do not. Using complementary tools plus careful study and interpretation of the original text and figures, we were able to rework, yet only partially replicate, this experiment. Reading peer-reviewed manuscripts that cited Holmes’ 1934 report provided an additional level of insight into the interpretation and replication of this work in the decades that followed. From this, we touch on how experimental reworking can inform our strategies to address the reproducibility “crisis” in twenty-first century science. (shrink)

I introduce a puzzle about contact and de re temporal predication in relativistic spacetime. In particular, I describe an apparent counterexample to the following principle, roughly stated: if B is never in a position to say ‘I was touching A, I am touching A, and I will be touching A’, then (time travel aside) A is never in a position to say ‘I was touching B, I am touching B, and I will be touching B’. In the case (...) I present, the most that A is ever in a position to say is: ‘I am now touching B, but this is the only instant at which this will ever be so’. B, on the other hand, can say: ‘I was formerly touching A, I am currently touching A, and I will in the future be touching A’. (And neither object is a time traveler.). (shrink)

Accession Number: ATLA0001712266; Hosting Book Page Citation: p 667-680.; Language(s): English; General Note: Bibliography: p 679-680.; Issued by ATLA: 20130825; Publication Type: Essay.

The Theory of Evolution has, since Darwin, been sustained by contributions from many sciences, most especially from molecular biology. Philosophers, like biologists and the man in the street, have accepted the idea that the contemporary form of evolutionary theory has arrived at a convincing and final structure. As it now stands, natural selection is thought to work through the information-handling mechanism of the DNA molecule. Variation in the genome?s constructive message is achieved through random errors of processing called mutations. How (...) that mechanism and its revision works, and how much information it can hold are fundamental questions for the Neo-Darwinian theory to face. It is argued here that neither the operation nor the data content of the genome, as science understand them, can underpin the role Darwinism assigns to natural selection. It follows that we cannot put our confidence in the explanatory force of Darwinian reasoning, but neither is there an alternative to it. (shrink)

It is tempting to explicate the mastery of language, as many philosophers have, with how we come to learn language. Interpreting how we come to learn a language necessarily involves saying what the mind's relevant capacities are. Too long we have been told that those capacities are adaptive to, as well as within, a social context; it seemed plausible to argue that we learn to have (propositional) thoughts as we learn and use the language conatively. This essay tries to persuade (...) the reader that there is something else besides, something that cannot be taught. That something, elusive as it is, is caught in one of the phrases with which the OED defines passion , 'An eager outreaching of the mind towards something'. Passion understood in this way is conceptually indispensable to human language. (shrink)

Man's belief in God is often contrasted with man's disbelief, Atheism; but the nature of human belief is contrastable with the nature of the belief of demons. A point of contrast lies in the consequences of the different sort of reasons men and demons must be understood to have. One consequence has to do with the vision of the world, seeing the world as God's creation, which men are expected to achieve and demons are not. The logic of the ?seeing (...) as? formula is explored and found wanting even though it seems inescapable in connection with human belief. In the end human belief appears more peculiar than demonic. (shrink)

On reading David Chalmers's book, The Conscious Mind (Oxford/New York: Oxford University Press, 1996), one is struck by the author's efforts to meet the difficulties and obscurities in understanding the human mind, as indeed most other philosophers have, by hazarding theories. Such undertakings rest on two broad, usually unexamined, assumptions. One is that we have direct access to our conscious minds such that pronouncements about it and its contents are descriptive. The other is that our actions have causal explanations which (...) incorporate beliefs, intentions, desires, etc . (propositional attitudes) as functional elements. These assumptions are questioned in this essay. They rest upon a notion of data which is out of place in explicating the mind. The conclusion reached is that we do not know our own minds because there are no data upon which such knowledge might be founded, and, consequently, there can be no responsible theories of mind. (shrink)

It seems to have been taken for granted that we all know what a human action is. However in attempting to draw from what philosophers have said about actions the necessary clues as to their distinguishing features, one finds little to discourage the idea that there is no way of distinguishing one category of occurrences, human actions, from the complex of different sorts of things which happen. From this I am tempted to conclude that there is no category of human (...) action. But before drawing such a conclusion an ancient but terrible question must be faced: What sorts of things happen in the world ? This ancient question is faced but not answered. It is brought up because the failure to find a satisfactory answer to the question, Is human action a category? is a failure even to find a satisfactory assumption about what kind of reference the term ?human action? is supposed to have. (shrink)

To say that a single human action can be given different descriptions is to imply that the contrast between action and description is intelligible. There are several ways in which such a contrast is easily understood, but those ways do not meet philosophers? needs. They have said that the descriptions are all true, thereby excluding that interpretation in which no more than one description could be true. They have emphasized the word ?different?, therefore that interpretation in which the descriptions are (...) partial and consequently combinable into one larger description is excluded. The descriptions must be different and true while remaining descriptions of the same single action. How can we conceive of this sort of contrast between description and action? It is not a familiar one. Several attempts are made in this paper to provide a way of conceiving of the contrast. All fail. The conclusion is hesitantly drawn that we have no other way to conceive of different human actions than by descriptions which are different from one another and true. (shrink)

The causal theory of action had suffered from inattention or linguistically motivated rejection until it was revived in 1963 by Donald Davidson. Since then the causal theory has had a continuing acceptance without having had an inspection of its assumptions. There are reasons to suspect that the theory is as unfounded as it is undoubted. Those reasons are reviewed here which have to do with the definitive moment when states such as beliefs and desires must change character to become causal (...) events. (shrink)

From obnoxious public figures to online trolling and accusations of “fake news”, almost no one seems able to disagree without hostility. But polite discord sounds farfetched when issues are so personal and fundamental that those on opposing sides appear to have no common ground. How do you debate the “enemy”? Philosophers Scott Aikin and Robert Talisse show that disagreeing civilly, even with your sworn enemies, is a crucial part of democracy. Rejecting the popular view that civility requires a polite and (...) concessive attitude, they argue that our biggest challenge is not remaining calm in the face of an opponent, but rather ensuring that our political arguments actually address those on the opposing side. Too often politicians and pundits merely simulate political debate, offering carefully structured caricatures of their opponents. These simulations mimic political argument in a way designed to convince citizens that those with whom they disagree are not worth talking to. Good democracy thrives off conflict, but until we learn the difference between real and simulated arguments we will be doomed to speak at cross-purposes. Aikin and Talisse provide a crash course in political rhetoric for the concerned citizen, showing readers why understanding the structure of arguments is just as vital for a healthy democracy as debate over facts and values. But there’s a sting in the tail - no sooner have we learned rhetorical techniques for better disagreement than these techniques themselves become weapons with which to ignore our enemies, as accusations like “false equivalence” and “ad hominem” are used to silence criticism. Civility requires us to be eternally vigilant to the ways we disagree. (shrink)

Graphical AbstractIdentifying the properties and molecules of the intestinal microbiome may help our understanding of various diseases and therefore facilitate their treatment; from excluding pathogens to manipulation of the immune system and regulation of non-intestinal sites.

This paper discusses the non-historicist structural ownership condition on moral responsibility forwarded by Benjamin Matheson. The structural ownership condition requires that a morally relevant action be grounded or partly grounded in psychological states that are generally coherent. While Matheson does not mean to settle the debate on historicism vs. non-historicism, he does mean to secure the position of the ownership condition against the problems that structuralist theories have faced in the past. This paper will focus on how the ownership (...) condition handles cases of ambivalent agents. Intuitively, ambivalent agents should be responsible for what they do as long as what they do is expressive of their cares or commitments, or their authentic character. At a first glance it appears that the ownership condition follows intuitions about ambivalence, but with a closer look we can see that Matheson has provided a potential counter example to this position. (shrink)

Hegel frequently claimed that the heart of his entire system was a book widely regarded as among the most difficult in the history of philosophy, The Science of Logic. This is the book that presents his metaphysics, an enterprise that he insists can only be properly understood as a “logic,” or a “science of pure thinking.” Since he also wrote that the proper object of any such logic is pure thinking itself, it has always been unclear in just what sense (...) such a science could be a “metaphysics.” -/- Robert B. Pippin offers here a bold, original interpretation of Hegel’s claim that only now, after Kant’s critical breakthrough in philosophy, can we understand how logic can be a metaphysics. Pippin addresses Hegel’s deep, constant reliance on Aristotle’s conception of metaphysics, the difference between Hegel’s project and modern rationalist metaphysics, and the links between the “logic as metaphysics” claim and modern developments in the philosophy of logic. Pippin goes on to explore many other facets of Hegel’s thought, including the significance for a philosophical logic of the self-conscious character of thought, the dynamism of reason in Kant and Hegel, life as a logical category, and what Hegel might mean by the unity of the idea of the true and the idea of the good in the “Absolute Idea.” The culmination of Pippin’s work on Hegel and German idealism, no Hegel scholar or historian of philosophy will want to miss this book. (shrink)

The notion of an individual and the related issues on individuation are topics that appear in the philosophical discussion ever since the antiquity. The idea of an individual thing is intuitively clear: an individual is something of a specific kind that is a unity, having its own identity, and being so that it is possible at least in principle to discern it from any other individual, even of similar species. But when we try to leave the intuitive realm and push (...) this idea to a logical analysis, we find a cluster of problems that are difficult to overcome within standard logico-mathematical contexts. In this work, we shall be concerned with some aspects of this intuitive concept of an individual and on some related facts about individuation taken from recent discussions that arose ever since the inception of quantum theory, pushing the discussion to a “logical” view, which in our opinion is still lacking in the usual debates on such issues. In the final part of the paper, we propose a metaphysics where the notion of identity is substituted, for some objects, by a weaker notion of indiscernibility, and we try to justify such a move. In most of the uses of the expression “quantum theory”, we shall not make explicit the distinction between the non-relativistic and the relativistic approaches, although they of course are quite different, for we think that the problems as we shall present them appear in both versions. But, as the text goes, the context will distinguish between them and these questions will become clear to the reader. (shrink)

Mitochondrial DNA (mtDNA) diseases are a group of neuromuscular diseases that often cause suffering and premature death. New mitochondrial replacement techniques (MRTs) may offer women with mtDNA diseases the opportunity to have healthy offspring to whom they are genetically related. MRTs will likely be ready to license for clinical use in the near future and a discussion of the ethics of the clinical introduction ofMRTs is needed. This paper begins by evaluating three concerns about the safety of MRTs for (...) clinical use on humans: (1) Is it ethical to use MRTs if safe alternatives exist? (2) Would persons with three genetic contributors be at risk of suffering? and (3) Can society trust that MRTs will be made available for humans only once adequate safety testing has taken place, and that MRTs will only be licensed for clinical use in a way that minimises risks? It is then argued that the ethics debate about MRTs should be reoriented towards recommendingways to reduce the possible risks of MRT use on humans. Two recommendations are made: (1) licensed clinical access to MRTs should only be granted to prospective parents if they intend to tell their children about their MRT conception by adulthood; and (2) sex selection should be used in conjunction with the clinical use ofMRTs, in order to reduce transgenerational health risks. (shrink)

Ned Markosian has recently defended a new theory of composition, which he calls regionalism : some material objects xx compose something if and only if there is a material object located at the fusion of the locations of xx. Markosian argues that regionalism follows from what he calls the subregion theory of parthood. Korman and Carmichael agree. We provide countermodels to show that regionalism does not follow from, even together with fourteen potentially implicit background principles. We then show that regionalism (...) does follow from five of those background principles together with and two additional principles connecting parthood and location, which we call and. While the additional principles are not uncontroversial, our conjecture is that many will find them attractive. We conclude by mentioning that fills a previously unnoticed gap in the formal theory of location presented in Parsons. (shrink)

[About the book] This book explores the idea that we have two minds - automatic, unconscious, and fast, the other controlled, conscious, and slow. In recent years there has been great interest in so-called dual-process theories of reasoning and rationality. According to such theories, there are two distinct systems underlying human reasoning - an evolutionarily old system that is associative, automatic, unconscious, parallel, and fast, and a more recent, distinctively human system that is rule-based, controlled, conscious, serial, and slow. Within (...) the former, processes the former, processes are held to be innate and to use heuristics that evolved to solve specific adaptive problems. In the latter, processes are taken to be learned, flexible, and responsive to rational norms. Despite the attention these theories are attracting, there is still poor communication between dual-process theorists themselves, and the substantial bodies of work on dual processes in cognitive psychology and social psychology remain isolated from each other. This book brings together leading researchers on dual processes to summarize the state-of-the-art, highlight key issues, present different perspectives, explore implications, and provide a stimulus to further work. It includes new ideas about the human mind both by contemporary philosophers interested in broad theoretical questions about mental architecture and by psychologists specialising in traditionally distinct and isolated fields. For all those in the cognitive sciences, this is a book that will advance dual-process theorizing, promote interdisciplinary communication, and encourage further applications of dual-process approaches. (shrink)

Relativity theory is often said to support something called ‘the four-dimensional view of reality’. But there are at least three different views that sometimes go by this name. One is ‘spacetime unitism’, according to which there is a spacetime manifold, and if there are such things as points of space or instants of time, these are just spacetime regions of different sorts: thus space and time are not separate manifolds. A second is the B-theory of time, according to which the (...) past, present, and future are all equally real and there is nothing metaphysically special about the present. A third is perdurantism, according to which persisting material objects are made up of different temporal parts located at different times. We sketch routes from relativity to unitism and to the B-theory. We then discuss some routes to perdurantism, via the B-theory and via unitism. (shrink)

After revelations of participation by psychiatrists and psychologists in interrogation of prisoners at Guantánamo Bay and Central Intelligence Agency secret detention centers, the American Psychiatric Association and the American Psychological Association adopted Position Statements absolutely prohibiting their members from participating in torture under any and all circumstances, and, to a limited degree, forbidding involvement in interrogations. Some interrogations utilize very aggressive techniques determined to be torture by many nations and organizations throughout the world. This paper explains why psychiatrists and psychologists (...) involved in coercive interrogations violate the Geneva Conventions and the laws of the United States. Whether done with ignorance of professional ethical obligations or not, these psychiatrists and psychologists have crossed an ethical barrier that may best be averted from re-occurring by teaching medical students and residents in all medical specialties about the ethics principles stemming from the 1946–1947 Nuremberg trials and the Geneva Conventions, together with the Ethics Codes of the World Medical Association and the American Medical Association; and, with regard to psychiatric residents and psychological trainees, by the teaching about The Principles of Medical Ethics With Annotations Especially Applicable to Psychiatry and the Ethical Principles of Psychologists and Code of Conduct, respectively. In this way, all physicians and psychologists will clearly understand that they have an absolute moral obligation to "First, do no harm" to the human beings they professionally encounter. (shrink)

We consider the desirability, or otherwise, of various forms of induction in the light of certain principles and inductive methods within predicate uncertain reasoning. Our general conclusion is that there remain conflicts within the area whose resolution will require a deeper understanding of the fundamental relationship between individuals and properties.

This article argues that we could improve the design of research protocols by developing an awareness of and a responsiveness to the social contexts of all the actors in the research enterprise, including subjects, investigators, sponsors, and members of the community in which the research will be conducted. ?Social context? refers to the settings in which the actors are situated, including, but not limited to, their social, economic, political, cultural, and technological features. The utility of thinking about social contexts (...) is introduced and exemplified by the presentation of a hypothetical case in which one central issue is limitation of the probability of injury to subjects by selection of individuals who are not expected to live long enough for the known risks of the study to become manifest as harms. Benefits of such considerations may include enhanced subject satisfaction and cooperation, community acceptance, and improved data quality, among other desirable consequences. (shrink)

Going back to Jacobi, commentators have often considered Kant’s notion of the transcendental object (thing in itself, monad, or object = X) to be concerned merely with empirical affection. Although most agree that this argument of Kant’s forbids the understanding from making illegitimate claims regarding the transcendental object, it is often assumed that no positive function can be ascribed to metaphysical illusions produced by reason. I will show in this paper, in contrast to most commentators, that a positive notion (...) of transcendental illusion is brought about by the cooperation of the imagination and reason in the latter’s pursuit of positing transcendental objects––in the same way that the imagination aids the understanding in determining objects of empirical cognition. When describing reason’s pursuit of systematicity, Kant writes that the transcendent ideas serve as a focus imaginarius that unifies cognition as such (A644/B672). It is not merely the case that metaphysical illusions regarding the soul, the world as such, and God are entirely useless, just because the understanding is prohibited from claiming having knowledge of such concepts.I take it that the transcendental object so considered in Kant’s Dialectic refers only to a representation of the imagination. I show that all three transcendental ideas––namely, God, the World as such, and the soul––are imaginary projections of unity carried out by the power of reason. Drawing on Kant’s notion of the focus imaginarius, I claim that reason regards transcendental illusions as being real objects. This holds as much for the schema of scientific knowledge, which is merely regulative, as it does for the three transcendental ideas. Unlike most commentators, I do not take Kant’s consideration of the transcendental object to concern empirical affection. Rather, reason posits this object in order to transcend the limits of the understanding, and to thereby use its own inner illusions for systematic purposes (cf. A250–53 and A393). To my mind, reason necessarily posits ideas, but the imagination often leads reason into holding that the focus imaginarius of the idea is an actual object. The critical use of reason must then put limits on the imagination (cf. A770/B798). But the imagination nonetheless serves reason’s interest by allowing it to put otherwise negative illusions to work for the sake of systematicity. (shrink)

We present a quantitative model of sex allocation to investigate whether the simple “rules of thumb” suggested by Trivers and Willard (1973) would really maximize numbers of grandchildren in human populations. Using demographic data from the !Kung of southern Africa and the basic assumptions of the Trivers-Willard hypothesis, we calculate expected numbers of grandchildren based on age- and sex-specific reproductive value. Patterns of parental investment that would maximize numbers of expected grandchildren often differ from the Trivers-Willard rules. In particular, the (...) optimum parental behavior is sensitive to population dynamics, type of parental investment, and, most important, relative ages of sons and daughters. It is doubtful whether a parent blindly following the simple Trivers-Willard rules would maximize numbers of expected grandchildren, on average. In addition, we show that sex-specific infanticide will almost never achieve the goal of maximizing expected numbers of grandchildren. (shrink)

Efforts to build research capacity and capability in low and middle income countries (LMIC) has progressed over the last three decades, yet it confronts many challenges including issues with communicating or even negotiating across different cultures. Implementing global research requires a broader understanding of community engagement and participatory research approaches. There is a considerable amount of guidance available on community engagement in clinical trials, especially for studies for HIV/aids, even culturally specific codes for recruiting vulnerable populations such as the San (...) or Maori people. However, the same cannot be said for implementing research in global health. In an effort to build on this work, the Pakistan Institute of Living and Learning and University College London in the UK sought to better understand differences in beliefs, values and norms of local communities in Pakistan. In particular, they have sought to help researchers from high income countries (HIC) understand how their values are perceived and understood by the local indigenous researchers in Pakistan. To achieve this end, a group discussion was organised with indigenous researchers at Pakistan Institute of Living and Learning. The discussion will ultimately help inform the development of a cultural protocol for researchers from HIC engaging with communities in LMIC. This discussion revealed five common themes; (1) religious principles and rules, (2) differing concepts of and moral emphasis on autonomy and privacy, (3) importance of respect and trust; (4) cultural differences (etiquette); (5) custom and tradition (gift giving and hospitality). Based on the above themes, we present a preliminary cultural analysis to raise awareness and to prepare researchers from HIC conducting cross cultural research in Pakistan. This is likely to be particularly relevant in collectivistic cultures where social interconnectedness, family and community is valued above individual autonomy and the self is not considered central to moral thinking. In certain cultures, HIC ideas of individual autonomy, the notion of informed consent may be regarded as a collective family decision. In addition, there may still be acceptance of traditional professional roles such as ‘doctor knows best’, while respect and privacy may have very different meanings. (shrink)

The term communism has long since been seen as largely derogatory, and the system it represents, a failure. Yet where do these notions of communism come from and are they reflective of the original ideals laid out by Karl Marx and Friedrich Engels? This paper will look at some of the divergences from Marx’ and Engels’ original intent to the form communism took in eastern Europe’s state-socialism. The analysis remains limited in scope with the intent of offering a rethinking (...) of how the works of Marx’ and Engels’ have been used and how it can still be used today. The issues seen within state-socialism and communism’s bureaucratism should not rob Marxist thought of all legitimacy. Instead, critically contemplating the original context and intent of the Manifesto can offer a renewed appreciation for their groundbreaking and radical work and remove some of the inherent prejudice against anything associated with socialism as being disproven and incompetent. The goal not being the re-establishment of socialism as a dominant force in the world today, but to ensure dialogue around issues do not settle on accepting the capitalist systems as some final form of social organization, but to continue to push for social improvement and equality. (shrink)

The temporal profile of dendritic branching in developing neurons is an interplay between the proliferating number of branching sites and the branching rates at these individual sites. The eventual metrical structure of dendritic arborizations is the outcome of joint processes of branching and elongation of outgrowing neurites. Dendritic growth models have shown to be powerful tools for quantitatively studying the rules of outgrowth, aiming at reproducing the shape characteristics in observed dendritic arborizations. Recent model studies, focusing on the branching process, (...) have predicted strongly decreasing branching rates during dendritic outgrowth. The implications of these findings for the metrical development of outgrowing dendrites will be discussed. (shrink)

On the surface, The Philosophical Hitchcock: Vertigo and the Anxieties of Unknowingness, is a close reading of Alfred Hitchcock’s 1958 masterpiece Vertigo. This, however, is a book by Robert B. Pippin, one of our most penetrating and creative philosophers, and so it is also much more. Even as he provides detailed readings of each scene in the film, and its story of obsession and fantasy, Pippin reflects more broadly on the modern world depicted in Hitchcock’s films. Hitchcock’s characters, Pippin shows (...) us, repeatedly face problems and dangers rooted in our general failure to understand others—or even ourselves—very well, or to make effective use of what little we do understand. Vertigo, with its impersonations, deceptions, and fantasies, embodies a general, common struggle for mutual understanding in the late modern social world of ever more complex dependencies. By treating this problem through a filmed fictional narrative, rather than discursively, Pippin argues, Hitchcock is able to help us see the systematic and deep mutual misunderstanding and self-deceit that we are subject to when we try to establish the knowledge necessary for love, trust, and commitment, and what it might be to live in such a state of unknowingness. A bold, brilliant exploration of one of the most admired works of cinema, The Philosophical Hitchcock will lead philosophers and cinephiles alike to a new appreciation of Vertigo and its meanings. (shrink)

This collection of thirty-one cases and commentaries addresses ethical problems commonly encountered by the average health care professional, not just those working on such high-tech specialties as organ transplants or genetic engineering. It deals with familiar issues that are rarely considered in ethics casebooks, including such fundamental matters as informed consent, patient decision-making capacity, the role of the family, and end-of-life decisions. It also provides resources for basic but neglected ethical issues involving placement decisions for elderly or technologically dependent patients, (...) rehabilitation care, confidentiality regarding AIDS, professional responsibility, and organizational and institutional ethics. The authors describe in detail the perspectives of each party to the case, the kind of language that ethicists use to discuss the issues, and the outcome of the case. A short bibliography suggests useful articles for further reading or curriculum development. Easily understood by readers with no prior training in ethics, this book offers guidance on everyday problems from across the broad continuum of care. It will be valuable for health-care professionals, hospital ethics committees, and for students preparing for careers in health-care professions. (shrink)

ExtractA few years ago, I, an American, was giving a talk at a political philosophy conference in the United Kingdom. My topic was religion in democratic politics, and I delivered what I thought was a splendid line of argument supporting the idea that religion has at most a highly constrained role to play in democratic politics. The audience was appreciative enough, but during the question and answer session, there emerged the charge that my paper had addressed a uniquely ‘American’ problem, (...) a problem that was not of general significance to political philosophers outside of the United States. I replied that although the political scene in the contemporary United States provides many high-profile examples of the problem I had been addressing, the general problem of religion in politics confronts democracy as such. I then provided some cases from outside America in which the problem shows itself: the public slaying of Theo Van Gough, the controversy surrounding the publication of cartoon representations of Muhammad in Denmark, the reemergence of religiously-affiliated and reactionary political parties throughout Europe, and so on. Yet for the most part my audience remained unmoved.Send article to KindleTo send this article to your Kindle, first ensure [email protected] is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle. Find out more about sending to your Kindle. Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply. Find out more about the Kindle Personal Document Service.RELIGION IN POLITICS: WHAT'S THE PROBLEM?Volume 12, Issue 33Robert B. TalisseDOI: https://doi.org/10.1017/S1477175612000279Your Kindle email address Please provide your Kindle [email protected]@kindle.com Available formats PDF Please select a format to send. By using this service, you agree that you will only keep articles for personal use, and will not openly distribute them via Dropbox, Google Drive or other file sharing services. Please confirm that you accept the terms of use. Cancel Send ×Send article to Dropbox To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about sending content to Dropbox. RELIGION IN POLITICS: WHAT'S THE PROBLEM?Volume 12, Issue 33Robert B. TalisseDOI: https://doi.org/10.1017/S1477175612000279Available formats PDF Please select a format to send. By using this service, you agree that you will only keep articles for personal use, and will not openly distribute them via Dropbox, Google Drive or other file sharing services. Please confirm that you accept the terms of use. Cancel Send ×Send article to Google Drive To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about sending content to Google Drive. RELIGION IN POLITICS: WHAT'S THE PROBLEM?Volume 12, Issue 33Robert B. TalisseDOI: https://doi.org/10.1017/S1477175612000279Available formats PDF Please select a format to send. By using this service, you agree that you will only keep articles for personal use, and will not openly distribute them via Dropbox, Google Drive or other file sharing services. Please confirm that you accept the terms of use. Cancel Send ×Export citation. (shrink)

Various aspects of the integrability of dynamical systems are discussed with the help of the singular point analysis. In particular the connection with the Painlevé property is described. Several examples will serve as illustrations.

This paper is a reply to criticism made by A. B. Cody ('Is ?Human Action?; a Category??, Inquiry, Vol. 14 [1971], No. 4) of earlier papers by the author ('On Describing Actions?, Inquiry, Vol. 13 [1970], Nos. 1?2, and ?Action?, No?s, Vol. 2 [1968], No. 2). For brevity, familiarity is presupposed not only with the three papers just mentioned, but also with Cody, ?Can a Single Action Have Many Different Descriptions?? Inquiry, Vol. 10 (1967), No. 2; R. E. (...) Dowling, ? ?Can an Action Have Many Descriptions?"?? Inquiry, Vol. 10 (1967), No. 4; and Cody, ?A Reply to Mr. Dowling?, ibid. (shrink)

Human development is meant to be transformational in that it aims to improve people's lives by enhancing their capabilities. But who does it target: people as they are or the people they will become? This paper argues that the human development approach relies on an understanding of personal identity as dynamic rather than as static collections of preferences, and that this distinguishes human development from conventional approaches to development. Nevertheless, this dynamic understanding of personal identity is presently poorly conceptualized (...) and this has implications for development practice. We identify a danger of paternalism and propose institutionalizing two procedural principles as side constraints on development policies and projects: the principle of free prior informed consent and the principle of democratic development. -/- . (shrink)

This chapter focuses on AI-based cognitive and perceptual enhancements. AI-based brain enhancements are already under development, and they may become commonplace over the next 30–50 years. We raise doubts concerning whether radical AI-based enhancements transhumanists advocate will accomplish the transhumanists goals of longevity, human flourishing, and intelligence enhancement. We urge that even if the technologies are medically safe and are not used as tools by surveillance capitalism or an authoritarian dictatorship, these enhancements may still fail to do their job (...) for philosophical reasons. In what follows, we explore one such concern, a problem that involves the nature of the self. We illustrate that the so called transhumanist efforts to “merge oneself with AI” could lead to perverse realizations of AI technology, such as the demise of the person who sought enhancement. And, in a positive vein, we offer ways to avoid this, at least within the context of one theory of the nature of personhood. (shrink)

Background: although cognitive behavioural therapy is the gold standard treatments for bulimia nervosa (BN) and binge eating disorder (BED), evidence for its long-term efficacy is weak. Empirical research support the efficacy of brief strategic therapy (BST) in treating BN and BED symptoms, but its statistical significance still need to be investigated. Objective: to statistically test the long-term efficacy of the BST treatment protocols for BN and BED through one-year post-treatment. Methods: a two-group longitudinal study will be conducted. Participants (...) class='Hi'>will be sequentially recruited for inclusion in a state-funded community psychotherapy clinic. Multilevel growth curve modeling will be used to estimate the average growth trajectories from baseline to one year after treatment termination for the severity of the BN and BED features as measured by the Eating Disorder Examination Questionnaire. Discussion: findings from this study will clarify the impact of BST in treating BN and BED symtoms. Conclusions: translating research into practice may inform how to ensure high-quality patient care. (shrink)

The Covid-19 pandemic has resulted in disruption of work and other social activities of so many people. Some were forced to stay at home and many decided to stay at home for fear of being infected with the virus. This phenomenon brought different reactions and even mental stress to many people. However, there were people who turned this kind of tragedy into creative work. This paper discusses the experiences and insights of known plant lovers in Digos City, Davao del Sur (...) Philippines. Digos City is one of the heavily affected places during the series of earthquakes that jolted Davao del Sur last year. While people are still recovering, COVID-19 added an additional burden to the residents. In this paper, we argue that their decision to focus on gardening was not only to fight boredom and to divert their attention during lockdown but this was their way of maintaining their well-being by participating in the on-going work of creation and recreation and to rise from the tragedy. We further argue that it might be good that this creative work will go beyond home gardening and beyond pots and slowly extend to creative work for environmental protection and preservation through more active engagements into reforestation activities. (shrink)

A hallmark of positive‐sense RNA viruses is the formation of membranous shelters for safe replication in the cytoplasm. Once considered invisible to the immune system, these viral shelters are now found to be antagonized through the cooperation of autophagy proteins and anti‐microbial GTPases. This coordinated effort of autophagy proteins guiding GTPases functions against not only the shelters of viruses but also cytoplasmic vacuoles containing bacteria or protozoa, suggesting a broad immune‐defense mechanism against disparate vacuolar pathogens. Fundamental questions regarding this process (...) remain: how the host recognizes these membranous structures as a target, how the autophagy proteins bring the GTPases to the shelters, and how the recruited GTPases disrupt these shelters. In this review, these questions are discussed, the answers to which will significantly advance our understanding of the response to vacuole‐like structures of pathogens, thereby paving the way for the development of broadly effective anti‐microbial strategies for public health. (shrink)